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Mechanisms of KCNQ1 gating modulation by KCNE1/3 for cell-specific function
Cui C*, Zhao L*, Kermani AA*, Du S*, Pipatpolkai T, Jiang M, Chittori S, Tan YZ, Shi J, Delemotte L, Cui J✝ and Sun J✝. Cell Research, 2025. (Preprint: doi: https://doi.org/10.1101/2025.06.08.658478)
Pharmacology of LRRK2 with type I and II kinase inhibitors revealed by cryo-EM
Zhu H, Hixson P, Ma W✝ and Sun J✝. Cell Discovery, 10:10, 2024
Structural basis of human NOX5 activation
Cui C*, Jiang M*, Jain N*, Das S, Lo Y, Kermani A, Pipatpokai T✝ and Sun J✝. Nature Communications, 15: 3994, 2024.
Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2
Zhu H*, Tonelli F*, Turk F, Prescott A, Alessi D and Sun J. Science, 382: 1404-1411, 2023.
Human IFT-A complex structures provide molecular insights into ciliary transport
Jiang M, Palicharla VR, Miller D, Hwang SH, Zhu H, Hixson P, Mukhopadyay S✝ and Sun J✝. Cell Research, 33: 288-298, 2023.
Structural analysis of the full-length human LRRK2.
Myasnikov A*, Zhu H*, Hixson, P, Xie B, Yu K, Pitre A, Peng J, Sun J. Cell 184:3519–3527, 2021.
Structures of mouse DUOX1–DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Sun J. Nature Structural & Molecular Biology 27:1086–1093, 2020
Structural Basis of Human KCNQ1 Modulation and Gating.
Sun J and MacKinnon R. Cell 180:340-347.e9, 2020.
Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Sun J and MacKinnon R. Cell 169(6): 1042-1050, 2017.
Crystal Structure of the Plant Dual-affinity Transporter NRT1.1.
Sun J, Bankston JR, Hinds TR, Payandeh J, Zagotta WN, and Zheng N. Nature 507(7490): 73-77, 2014.
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